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BELOTERO® is a range of hyaluronic acid dermal fillers with optimal tissue integration1. It can be used to fill out fine, moderate and severe wrinkles and nasolabial folds, as well as to restore facial volume. The BELOTERO® range of fillers is available with lidocaine to reduce the sensation of pain and improve comfort.

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How It Works

BELOTERO® Fillers use a patented CPM® (Cohesive Polydensified Matrix) technology for optimal tissue integration1. While the standard cross-linking process of most fillers only consists of three phases, BELOTERO® Fillers are manufactured using Dynamic Cross-Linking Technology (DCLT) that includes two additional phases. This advanced technology provides each BELOTERO® Filler with a combination of cohesivity, elasticity, and plasticity to match the needs of the targeted layer of the skin.
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FAQs

What is Belotero® used for?

Belotero® Soft Lidocaine is an injectable biodegradable implant intended for filling of perioral fine lines.

Belotero® Balance Lidocaine is an injectable biodegradable implant intended for filling of moderate facial wrinkles and folds as well as for lip enhancement.

Belotero® Intense Lidocaine is an injectable biodegradable implant intended for filling of deep facial wrinkles and folds as well as to restore and enhance soft tissue volume.

Belotero® Volume Lidocaine is an injectable biodegradable implant intended for correcting signs of facial fat loss (lipoatrophy) in patients with human immunodeficiency virus. Belotero® Volume Lidocaine is also intended for restoration of facial volumes.

The presence of lidocaine aims to reduce local pain associated with the injection of the gel and to improve patient comfort.

How long do Belotero® results last?

The results of Belotero® typically last for between 6 – 18 months depending on the specific type of filler injected, but are not permanent. Duration depends on many factors such as the area being treated, skin type, skin condition, metabolism, lifestyle, and age. After the initial treatment, follow-up sessions are normally recommended.

How much time does the treatment take?

During the treatment session, the product is injected into the specific area of the face to be treated, typically using a fine needle or cannula. The treatment is quick, usually taking about 30 minutes, but might take longer if multiple areas are being treated in the same session.

What can I do to obtain the best possible results after injection?

Avoid applying makeup during the first 12 hours after treatment. Avoid saunas, hot tubs, prolonged exposure to the sun, UV rays, and extreme cold temperatures for two weeks after treatment. After the initial treatment, follow up sessions are normally recommended. During your follow up visit, your Healthcare Practitioner may decide to inject more product in order to improve the appearance of the initial treatment.

How long is recovery time?

There is little to no downtime associated with a Belotero® treatment. In fact, most patients return to their normal, daily activities right after their visit. Every patient is unique, so be sure to discuss your plans during the consultation with your Healthcare Practitioner.

Does the treatment hurt?

There may be slight discomfort whilst the filler is being injected into the skin but it can be reduced with the application of an anaesthetic cream or injection of local anaesthesia before the treatment to provide greater comfort and relief. The Belotero® range of fillers is available with lidocaine to reduce the sensation of pain and improve comfort.

Are the effects temporary or permanent?

Hyaluronic Acid is completely broken down within the skin over a period of months, eventually leaving no trace of the filler. It is also reversible – if your Healthcare Practitioner decides to dissolve the material, he/she can do so by introducing an enzyme called hyaluronidase to dissolve it. However, the enzyme should be used with caution and please inform your Healthcare Practitioner should you have any form of allergies.

Are there any risks or side effects?

Most adverse reactions are injection-site related and often transient. These include slight redness, swelling, itching, bruising, and pain at injection sites. They are generally mild to moderate in severity and disappear on their own shortly after injection (typically within one or two days).

Less common reactions such as inflammation, infection, fistulisation, hardening, and slight discolouration of the treated areas may also occur. If you suffer from poor wound healing, delayed healing may occur. Rare but serious adverse events associated with the intravascular injection of soft tissue fillers in the face have been reported and include temporary or permanent vision impairment, blindness, cerebral ischemia or cerebral hemorrhage, leading to stroke, skin necrosis, and damage to underlying facial structures.

Prior to treatment, your Healthcare Practitioner will inform you about the possible risks and side effects.

Are there any reasons I should not be treated with Belotero®?

You should avoid treatment if you have an allergic reaction to any of the ingredients. If you tend to develop keloids or granulomas, or have inflamed or infected skin, you should forego treatment. Belotero® should not be injected over permanent implants. Please inform your Healthcare Practitioner before treatment if you are taking anticoagulants. He or she can decide whether a treatment is suitable for you. If you suffer from a systemic disease (autoimmune disease, diabetes, rheumatism or endocarditis), please inform your practitioner so that you can decide together whether a treatment is advisable for you. As there have been no experiences with pregnant women, breast-feeding mothers or adolescents under 18 years of age, these groups of people should not be treated with Belotero®.

  1. Tran C, et al. In vivo bio-integration of three hyaluronic acid fillers in human skin: a histological study. Dermatology. 2014;228(1):47-54